Preclinical research services are a range of services offered by contract research organizations (CROs) and academic research institutions to support the development of new drugs and therapies before they enter clinical trials in humans. These services are typically used by pharmaceutical and biotech companies to evaluate the safety, efficacy, and pharmacology of their drug candidates in vitro and in vivo using animal models.
Some of the preclinical research services offered by CROs and research institutions include:
- Pharmacology and toxicology studies: These studies evaluate the pharmacological activity and toxicity of a drug candidate in vitro and in vivo, including its effects on organs, tissues, and physiological functions.
- Pharmacokinetics and bioanalysis: These studies evaluate the absorption, distribution, metabolism, and excretion (ADME) of a drug candidate in vitro and in vivo, including its pharmacokinetic properties and bioavailability.
- In vivo efficacy and disease models: These studies evaluate the efficacy of a drug candidate in animal models of disease, such as cancer, cardiovascular disease, and neurological disorders.
- In vitro screening and assays: These studies evaluate the effects of a drug candidate on specific cellular and molecular targets using biochemical and cellular assays.
- Formulation development: These services involve developing and optimizing the formulation of a drug candidate to improve its stability, solubility, and bioavailability.
- Regulatory support: CROs and research institutions can provide assistance with regulatory submissions and compliance with regulatory guidelines for preclinical research.
Preclinical research services are critical for the development of new drugs and therapies, providing valuable insights into the safety, efficacy, and pharmacology of drug candidates before they are tested in humans. They can also help to identify potential issues and challenges that may arise during clinical trials, allowing companies to address these issues before investing significant resources in clinical development.
